Pandorum Technologies Raises US$18 Million in Series B to Advance Global Access to Programmable Tissue Regenerative Therapies
Funding accelerates clinical development and market access across the U.S., Asia, and the Middle East
Pandorum Technologies a biotechnology company pioneering programmable regenerative medicine, with operations in India and the United States, has announced the closing of a US$18 million in Series B financing round, to advance the clinical development of its disease-modifying, tunable, exosome-based therapies, including Kuragenx, while scaling global manufacturing and expanding operations across the U.S., Japan, and the Middle East.
The round was led by Protons Corporate, with participation from Galentic Pharma, marquee investor Ashish Kacholia, Noblevast Advisory and Avinya Fund, Burman Family and others. Bandan Kankani, advisor and investor at Pandorum, had guided the transaction, optimizing the alignment between the investment architecture and company’s value creation.
Founded by Tuhin Bhowmick and Arun Chandru, Pandorum’s proprietary platform combines biology, engineering, and computation to develop tunable, regenerative exosome therapies that reprogram pathological tissue states, like inflammation and fibrosis, toward functional recovery.
“Just like the Ship of Theseus, the human body is constantly being rebuilt. Pandorum focuses on restoring biological memory, redefining regenerative medicine at its core,” said Dr. Tuhin Bhowmick, Co-Founder and CEO of Pandorum. “Our approach treats tissue health, disease, and degeneration as a navigational challenge within an information-constrained biological landscape,” added Dr. Tuhin. “This funding would enable us to translate breakthrough science into programmable, disease-modifying therapies, beginning with single-tissue applications and scaling to multi-tissue repair, aligned with Pandorum’s vision- to heal fast and age slow.”
“Congratulations to our team for this achievement. Regenerative medicine, particularly for corneal blindness, is a global necessity that knows no borders,” said co-founder Arun Chandru.
The clinical translation efforts are led by globally recognized clinicians, including Dr. Virender Singh Sangwan (Dr. Shroff’s Charity Eye Hospital, New Delhi), Dr. Shigeru Kinoshita (Kyoto Prefectural University of Medicine, Kyoto), and Dr. Ramez Haddadin and Dr. Satish Nadig (Northwestern Medicine, Chicago).
Pandorum has implemented a globally distributed manufacturing strategy, including a CDMO partnership with AGC Biologics (Italy) for the U.S. and European markets, and a strategic collaboration with Nucelion Therapeutics (India), a subsidiary of Bharat Biotech, to support supply across the Asia-Pacific region. The company is also exploring potential partnerships in the Middle East.
Pandorum’s primary focus is on ocular surface diseases, such as Stevens–Johnson Syndrome and Neurotrophic Keratitis, for which Kuragenx has received U.S. FDA Orphan Drug Designation. In addition to ophthalmology, it is expanding its tunable platform to address systemic conditions, including inflammatory and degenerative diseases affecting the lung, liver, and nervous systems.
About Pandorum Technologies
Pandorum Technologies is an Indian biotechnology startup company known for pioneering 3D Bio-printed human tissues, including lab-grown mini-livers and bio-engineered corneas. It is into tissue engineering and regenerative medicine. The company operates research facilities in India, and the U.S.
- 3D-Printed Mini-Liver (2015): Pandorum became the first Indian firm to 3D-bio-print functional human liver tissue. This innovation helps pharmaceutical researchers test drug metabolism and toxicity while reducing animal testing.
- Liquid Cornea and Corneal Lenticules (2019): The company developed a specialised hydrogel and 3D-printed transparent corneal tissue designed to treat blindness, promote scarless healing of corneal wounds, and enable future human implantations.
- Translational & Animal Studies (2022): Progress continued with advanced studies and successful animal trials on bioprinted corneal tissue, paving the way for eventual human clinical applications.
- On-Demand Organs: Founded by alumni of the Indian Institute of Science, Pandorum’s long-term roadmap aims to scale up cell-printing capacity significantly toward 2030 to build fully functional, transplantable human organs like livers, kidneys, and lungs.
Source : Pandorum Technologies
